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Boron containing compounds have not been widely studied in Medicinal Chemistry, mainly due to the idea that this group could confer some toxicity. Nowadays, this concept has been demystified and, especially after the。

Organoboron compounds, including boronic acids, borinic acids and borane derivatives can be prepared by the addition of an organometallic species onto trialkoxyborane。

The interaction of boronic acids with diols or anions has been intensively investigated 6,7,8,9,10 and boronic acids have been exploited in a range of applications as。

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